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"Mike was able to use his informatics background to dig into the underlying mechanisms.
This might be a very hectic task, especially for a person with no informatics background.
During the scientific solution deployment and usage, the end user is probably a scientist without strong informatics background.
If a person with an Informatics background cannot easily configure and use Bioinformatics solutions then how can a layman.
UA and IRC supervised the work; UA supplied the informatics background and the algorithms and IRC provided the immunology and contributed the biologic interpretations; IRC also wrote the text of the paper.
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Using the HCI design patterns and principles, the graphical user interfaces of all these applications were designed considering the psychology, scientific and informatics backgrounds of the end users and the deployment environments.
Raw data were first imported into a Genetraffic duo database (Iobion Informatics, Toronto, Canada), local background-subtracted and normalized using a Lowess (locally weighted linear regression) transformation.
This paper is organized as follows: Section "Big data in health informatics" provides a general background on Big Data in Health Informatics.
The project was assigned to a team of four members with background in informatics, applied computer science and educational science and technology.
Our multidisciplinary team includes clinicians, doctoral level informatics researchers with different backgrounds, and medical anthropologists.
With the advent of Next generation sequencing, the work is increasingly automated in an informatics process running in the background from the point of view of biologists and thus getting out of view from their perspective, further naturalising the meaning of connections between in silico sequences and living bodies.
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