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This informatics analysis is a new trial to identify exon-level annotations.
In addition, an informatics analysis showed that a large set of host genes could be potentially targeted by TMV-Cg-derived siRNAs for posttranscriptional silencing.
To explore this possibility, an informatics analysis to systemically identify the potential host targets was performed for each of the 21-nt computationally generated TMV-Cg siRNAs.
Although this informatics analysis is a new trial to identify exon-level annotations, it is likely that insufficient researches has been performed on splicing isoforms.
Thus, data derived from multiple proteomics platforms and transcript data coupled with informatics analysis provides a deeper insight into the functional consequences of androgen action in prostate cancer.
The recent large-scale informatics analysis of 62 bacterial T4SSs revealed a highly conserved core set of T4SS components (VirB6, VirB8-VirB11, VirD4) coupled with a depauperate complex of the remaining Vir components, of which the latter were suggested to have been acquired in various independent events [29].
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These were previously employed by Sutherland et al. in a comparative study of QSAR methods commonly used in chemo-informatics analysis [23] and since then, these have been utilized as "benchmarks" for comparing results obtained in other approaches [43 47].
It is thus important that new informatic analysis platforms are developed that allow the organization and interrogation of Big Data resources into a rational and actionable mechanism for advanced therapeutic development.
The bio-informatics analysis also detected the putative acquisition of pilA and mexC from Acinetobacter baumannii and Pseudomonas aeruginosa, respectively.
This study demonstrates that ESTs provide a resource for SNP identification in non-model species, which do not require any additional bench work and little bio-informatics analysis.
Informatic analysis yielded profound evidence for degeneration and loss of muscle specific genes.
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