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These data inform the functions of two genes not associated previously with human genetic disease and demonstrate how CNVs can exhibit complex genetic architecture, with the phenotype being the amalgam of both discrete dosage dysfunction of single transcripts and also of binary genetic interactions.
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What's going on in all of these cases, and how can our understanding of these extremes of human memory inform the function of memory in all of us?
Structural analyses of such domains by nuclear magnetic spectroscopy or X-ray crystallography may greatly inform the function of proteins.
Because most of its genes have homologues in other organisms, our understanding of how the proteins that they encode carry out the basic functions of a cell informs the functions of their counterparts in other organisms, including humans.
However, although this method informs the function of the trait, it does not say much about the genetic mechanisms that shape this trait.
Together, these sex-related changes in kidney gene expression during the rat life cycle expand current understanding of kidney function and inform the use of current and proposed safety biomarkers.
While expression patterns alone do little to inform the precise functions of genes, similar expression of orthologous genes across related phyla often reflects conserved functional relationships.
The weak correlation between interaction numbers and sequence identity and the relatively strong function prediction power of considering both sequence identity and interaction numbers suggest that they are two rather independent factors informing the function similarity of two genes.
Advances in understanding one LGI family member may inform us about the functions of others.
In this study, we primarily focused upon particle transport speed because it not only informs about the function of individual ciliated cells but takes into account the coordinated function of many cells and thus more closely reflects the in vivo situation.
For designers, Grain should inform the prioritization of functions, reflect on hierarchy, and provide order to a user's movement through time.
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