Sentence examples for influx systems from inspiring English sources

Alternatively, metal acquisition might occur nonspecifically in some of these organisms using cation influx systems.

Influx systems of metal ions in cells are strongly regulated by both transcriptional and posttranscriptional control mechanisms [ 25].

As antifolates are hydrophilic drugs, which cannot transverse the plasma membrane, they rely on specific influx systems for their cellular uptake and pharmacologic activity.

The related LHT1 (At5gene80) gene which appears to encode a high-affinity glutamate influx system [ 45] was also moderately downregulated in glu1-2 roots but not affected in glu1-2 leaves.

In all of these cases, a high rate of Ca2+ uptake via upregulation/activation of a high-affinity Ca2+ influx system that involves Cch1p and Mid1p is triggered.

We next analysed whether the rise in basal [Ca2+]cyt triggered by αSyn is connected to the upregulation of a specific Ca2+ influx system that has been shown to be stimulated in scenarios such as the accumulation of misfolded proteins in the endoplasmic reticulum, different defects in vesicular trafficking and depletion of Ca2+ from the endoplasmic reticulum, for example, upon PMR1 deficiency.

ENA1-independent mechanism may involve other cation efflux systems, such as NHA1 and SNQ2 or K+-influx systems like TRK1 [59] [60], [60].

Therefore, few drugs, which maintain blood to brain influx transport systems, for example, an amino acid transporter Lat1/SLC 7andand organic cation transporter, show CNS delivery [ 216].

The efflux and influx transporter systems of BBB comprise transporters like ATP-binding cassette (ABC) transporters and solute carrier (SLC) transporters.

Optimizing the TJ tightness of hCMEC/D3 cell monolayers still remains a major challenge in order to provide an in vitro model that might recapitulate all the characteristics of human BBB, encompassing permeability restriction with appropriate molecular exclusion and functional efflux and influx transport systems.

We find that either scenario is plausible, although the influx-driven system is inherently more stable.