Sentence examples for influx channel from inspiring English sources

Active STIM1 will be translocated to the ER-plasma membrane junction [ 67], opening the Ca2+ influx channel ORAI1 [ 68, 69].

This could be due to hyperglycemia-mediated endothelin-1 resistance and calcium influx channel inhibition in smooth muscle cells.

This hyperpolarization is indispensable for T cells, apparently lacking depolarization Ca2+ channels (see below), where CRAC (SOCE) is believed to be a central Ca2+ influx channel.

The CRAC channel activation involves physical migration of ER-resident STIM to ER plasma membrane junctions and subsequent aggregation of the Ca2+ influx channel.

Lateral polarity of plasma membrane transporters has been previously demonstrated in rice for the Low silicon rice 1 (Lsiliconlinfluxnflux channel and the Low silicon rice 2 (Lsiliconlicon exporter localized at the outer and the inner polar domain of the plasma membrane, respectively.

Upon stimulation by extracellular transmitters and hormones, activation of Ca2+ influx channels in the plasma membrane (PM) or Ca2+ release channels in the ER, such as inositol 1,4,5-triphosphate receptors (IP3Rs) and ryanodine receptors (RyRs) (Clapham, 2007; Berridge, 2012), leads to rapid [Ca2+]cyt increases of 10 100 fold to μmol/L concentrations.

Tosun et al. found that both L-type and non-L-type Ca2+ influx channels could account for thromboxane A2 receptor-mediated contraction in rat aorta, but the identity of the non-L-type calcium channel is unclear (1998).

With respect to the former concept, it has been suggested that electromagnetic fields can promote Ca2+ signals by changing the phase, or packing, of membrane lipids, or by somehow directly modulating Ca2+ influx channels [33], [34].

This suggests that the activation of KCa3.1 channels by Ca2+ under physiological conditions relies on a tight spatiotemporal Ca2+ signal provide by Ca2+ influx channels.

Both potassium and thapsigargin lead to elevated levels of Ca2+, by activating Ca2+ influx channels and depleting intracellular Ca2+ storage, respectively (Pulver-Kaste et al., 2006).

The findings and implication for two Ca2+ influx channels in glioma, SOC (this work) and P2X7R [ 16], are considered in more detail below.