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Alcoholism is a complex disease caused by a confluence of environmental and genetic factors influencing multiple brain pathways to produce a variety of behavioral sequelae, including addiction.
Procambarus clarkii is an invasive crayfish influencing multiple features of invaded wetlands, but unravelling its impact on organisms with complex life cycles is difficult.
Therapeutic approaches therefore need a target influencing multiple signaling pathways or functions, e.g. transcription factors, second messengers, or peptidases in order to reflect the polygenetic character of obesity.
Moreover, given the pleiotropic effects caused by the mutational inactivation of VosA and VeA [15] [18], these regulators may act globally at a higher hierarchic level influencing multiple biological processes.
Interestingly, we observed that the signal intensities for phospho-IGF-1R and total IGF-1R were also decreased on the protein array, which raised the possibility that PTK6 modulates activation and/or expression of the receptor itself, thereby influencing multiple downstream signaling molecules.
Ageing is a complex process influencing multiple mechanisms and physiological systems.
Similar(31)
The InTeGrate project sought to influence multiple domains within an interconnected model of professional growth.
However, changes in species diversity can simultaneously influence multiple interdependent ecosystem functions.
Prolactin (PRL) is a multifunctional hormone that influences multiple physiological processes.
The derived transition function is generally a full matrix, because changes in load and generation buses influence multiple SVs.
AS exposures remarkably influenced multiple pathways including RNA transport, the spliceosome, RNA degradation, p53 signaling and MAPK [123].
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