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Fork passage likely contributes to reset the epigenetic landscape, influencing gene expression and transcriptional memory.
Transcription factors (TFs) direct developmental transitions by binding to target DNA sequences, influencing gene expression and establishing complex gene-regultory networks.
Regulatory variation influencing gene expression is a key contributor to phenotypic diversity, both within and between species.
Furthermore, we show that haplotype variants and allelic interactions have differential effects on chromosome configuration, influencing gene expression, and may provide mechanistic insights into functions associated with disease susceptibility.
On a molecular level, EMT is defined by several intermediates responsible for influencing gene expression.
The environment is a potent genetic modifier, influencing gene expression via epigenetic mechanisms.
Testosterone, like all steroid hormones, exerts its effects by influencing gene expression.
In addition, other factors such as differences in miRNA expression profiles could also be influencing gene expression.
Combinatorial arrangement of histone modifications determine the local packaging of the DNA, thereby influencing gene expression [127].
Of note, environmental factors can further complicate the genotype-phenotype relationships by influencing gene expression in leukocytes [55].
These relationships are not explained by our current understanding of the role of genic noncoding sequences in regulating or influencing gene expression.
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