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Overall, these effects are mild compared to the drastic effects on Brachyury and cardiac gene expression, suggesting that the primary role of Wnt/β-catenin signaling in this context is in driving differentiation rather than influencing cell death or proliferation.
Systems biology tools (physical protein-protein interaction [PPPI] network) were applied to analyse the propolis-induced transcriptional bevavior, aiming to identify which pathways are modulated by propolis in S. cerevisiae and potentially influencing cell death.
Accumulating evidence has recently demonstrated that SIRT3 may function as either oncogene or tumor suppressor on influencing cell death by targeting a series of key modulators and their relevant pathways in cancer.
In the presented study of A. nidulans, the fungal ATM homolog was shown to control mitochondrial mass and function, which directly or indirectly influenced glucose uptake while also influencing cell death in response to carbon starvation.
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These data suggest that NO can influence cell death by modulating NF-kappaB activity with the sites of inhibition being cell type-specific.
Altogether these gene expression modulations might influence cell death or tumor invasiveness.
These results show that IFNγ influences cell death in NPCs by influencing a subset of death-regulating proteins including PUMA with the activation of caspase-3.
The elatomer O-rings completely blocked the leakage of culture media, and PCBs that can influence cell death were isolated from NSCs and culture media.
It has been identified to be associated with the cytoplasmic domain of the FAS receptor, although its activity was not found to influence cell death directly [59].
To test whether genetic enforcement of respiration influences cell death during seeding of a cell population (which is the chronological step before a colony establishes), media-shift experiments using glucose (SCGlu), galactose (SCGal), and glycerol (SCGly) media as alternating sole carbon sources were performed.
However, BH3 mimetics not only influence cell death, but also senescence, autophagy or ER stress responses.
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