In addition to shedding light on how different ways of processing numerical information influences risk judgments and willingness to act, this research has important implications for crafting messages designed to communicate risk.
However, others concluded that there was insufficient evidence that ALA influences risk factors for CVD [15], [16].
Taken together, our multi-ethnic replication study suggests that IL12B sequence variation influences risk for pulmonary PTB either directly or through LD with a functional variant.
In addition, and central to the understanding of cancer progression, common risk alleles showed differential influence according to ERα tumor status [12], and variation in the locus encoding for ERα, ESR1, also influences risk of breast cancer [13], [14].
Nevertheless, a significant bias was still observed following exclusion of these two loci (GSEA nominal P = 0.001; FDR-adjusted P = 0.048), which suggests that variation at additional driver kinase loci influences risk of breast cancer.
Common genetic variation in loci encoding for FGFR2 and MAP3K1 influences risk of breast cancer [2], [4], and these genes were previously found to be somatically mutated in diverse neoplasias including breast cancer [10], [11].
