Sentence examples for influences its binding from inspiring English sources

PolyQ expansion of ataxin-1 also influences its binding to RNA [18] and in this manner could alter its suggested role in nucleocytoplasmic shuttling of mRNA [7], a process that is very important for local translation of proteins in neurons.

14 Previous studies have also shown that the diversity in the EPIYA-repeat region of CagA influences its binding ability to SHP2 and PAR1b.

However, in metallo-proteins, an internal metal ion often is coordinated by charged residues and hence the overall charge on the molecule is influenced by the neighboring side-chain groups which give the protein a varying net charge depending on the pH of the solute, which influences its binding and elution in an ion exchange column [ 22].

Interestingly, sialylation of OPN has been shown to influence its binding properties (Shanmugam et al, 1997).

GATA3 interacts with tyrosine-phosphorylated T-bet, negatively influencing its binding to DNA and thus antagonizing Th1 differentiation [ 78].

Since acetylation, phosphorylation, and oxidation induce changes in charge and conformation of HMGB1, they might influence its binding to different polymers.

Streptomycin also interacts with ribosomal proteins in the 30S subunit 49, 50 and mutations in S4, S5 and S12 ribosomal proteins are shown to influence its binding.

Next to the physicochemical parameters of the adsorbent polymers, modifications of HMGB1 are likely to influence its binding to different polymers.

The same may hold true for HMGB1 (30 kDa), and as discussed further below, its association with a wide range of plasma proteins as well as with microvesicles may additionally influence its binding characteristics.

With GPS-SNO 1.0, we predicted that p53 might be nitrosylated at C135 (Figure 5A), which locates in the DNA binding region of p53, potentially influences its DNA binding affinity and regulates p53 subcellular localization (Figure 5A).

However, the hydrophobicity of the nanoparticle strongly influences its protein binding properties [1], [5].