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In summary, spatially and evolutionarily conserved IDRs in kinases may influence their functions, which can be exploited for targeted therapies in diseases including those that involve aberrant cytoskeletal remodeling.
In the central nervous system neurons and glial cell heavily interact and mutually influence their functions [ 45].
For membrane-anchored growth factors, ectodomain shedding can convert them into diffusible factors and greatly influence their functions.
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Hence, this review aims to summarize the current knowledge of mapped mutations and other structural information on XP proteins that influence their function and protein protein interactions.
Up to date, those NP-CIK cells in liver, spleen, lung, and kidney organs show how to influence their function, which is not still clear, and needs further investigation.
In this study, we report the use of microbubble technology as a means to culture cells in a controlled microenvironment in which cells can influence their function through autocrine signaling.
Coastal ecosystems and artisanal fisheries show a great complexity due to the high number of human factors that influence their functioning and to the number of components involved in the fishing activity.
Knowledge at the atomic level is essential to understand and influence their function.
It is well established that the interactions of HSCs with the bone marrow microenvironment can significantly influence their function and fate [17].
Although the precise role of gp130 in hematopoietic stem/progenitor cells is not fully understood signalling via gp130 is important in the expansion of fetal definitive hematopoiesis [33], [34], and appears to influence their function both in vivo and in vitro [35] [38].
For example, various surgical tools have different capabilities and limitations that influence their function.
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