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Exactly how area-based socioeconomic conditions influence the stage at which an individual is diagnosed with breast cancer is complex.
First, to what extent might the reduced recognition of early cancer symptoms in people with mental disorders influence the stage of cancer at diagnosis?
There may also be selection on modifiers of recombination that influence the stage of meiosis at which distorters gain a transmission advantage (Haig 2010; Brandvain and Coop 2012).
This data suggests that aberrant regulation of these TFs (NFKB, AP1, STAT3, TP53, TP63 and MYC) could potentially influence the stage II CRC progression.
International or regional differences in survival could be at least partly attributable to cultural differences that influence the stage at which disease is diagnosed, as well as to the different ways in which national health care systems are organized.
Over the past several decades, MRI has been used to assess the extent of NPC more reliably and accurately compared with CT, which has been shown to influence the stage assignment and disease prognosis [ 28– 30].
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Previous works demonstrated that MuSC interactions with FAPs regulate the ability of skeletal muscle to undergo either regeneration or fibroadipogenic degeneration (Joe et al, 2010; Rodeheffer, 2010; Uezumi et al, 2010) and suggest that FAPs/MuSCs interactions might also influence the stage-specific response to HDACi in mdx mice (see Figs 1 and 2).
All these findings can profoundly influence the staging and management of the patient with head and neck cancer.
Furthermore, the presence of ulceration, large size, location of the tumor and diffuse type histology are important factors that influence the staging accuracy of EUS[ 34 36].
It should also be kept in mind that biological events are not always strict and thus the proposed sequential development of pathology might be altered by a variety of factors and thus influence the staging results.
Their five decades of history is one soaked in more colors than red and has influenced the stage and screen.
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