In the context of genetic association studies, strongly relevant variables with respect to a phenotype represent the genetic and phenotypic factors that directly influence the phenotype (e.g. disease susceptibility).
Based on the distribution of lsSNPs, we found certain regions and genes that were different between the mother line and its descendants and subsequently may influence the phenotype.
Our hypothesis was that the murine gut microbiota varies among different distributors of laboratory animals and that these variations influence the phenotype of abdominal sepsis derived from a bacterial inoculum model (intraperitoneal stool injection).
A gene is a sequence of DNA that contains genetic information and can influence the phenotype of an organism.
This result demonstrates that the overall growth conditions can influence the phenotype of sec9 mutants.
In addition, we examined if the antigen dose could influence the phenotype of the induced T cells.
Similarly, although interclonal sequence diversity in P. aeruginosa is on the average just 0.5% [8], [86], subtle genetic differences may strongly influence the phenotype of complex traits.
The availability of genome-wide genotype data provides the opportunity to conduct a comprehensive and unbiased survey of genetic determinants that could influence the phenotype [6], [7], [8].
Maternal phenotype does however influence the phenotype of offspring (paternal phenotype does not), consistent with weak inheritance of the epigenetic state through the female germline [13], [15].
The genetic background of these hybrid strains could influence the phenotype; however the strains used here are derived from standard laboratory strains.
The gld mutation did not influence the phenotype of DN T cells in the gut epithelium, as the surface profiles of DN T cells in the gut of wt and gld mice were comparable (Fig. 4A, middle and right panels).
