Sentence examples for influence the folding from inspiring English sources

The purpose of this work is to show how mutation, truncation, and change of temperature can influence the folding kinetics of a protein.

This would be very helpful for medical purposes and technological applications in nanobiology, but will require an understanding of various factors that influence the folding of the polypeptide and their sequence determinants.

Their general ease of expression and refolding and straightforward methods to monitor their degree of folding conspire to make OMPs excellent model systems to investigate how the membrane environment and other biological factors modulating the membrane insertion and folding of OMPs influence the folding pathway.

For example, in 2011 Folding@home simulated protein folding inside a ribosomal exit tunnel, to help scientists better understand how natural confinement and crowding might influence the folding process.

Glycosylation can influence the folding of proteins, their biological activity and half-life.

The modeled structure has three domain architecture and this conformation is stabilized by the presence of a large number of tryptophan residues which in the absence of disulphide bonds influence the folding due to their predominantly hydrophobic nature.

Here, we ask which intracellular components or processes of the pathway can contribute to the different dynamics of NF-κB upon stimulation and if those intracellular components or processes may also influence the fold change of NF-κB.

It therefore appears that variations in the two parameters, total NF-κB concentration or the transcription rate constant of IκBα, do not only lead to changes in the dynamical behaviour but also influence the fold change of active NF-κB (compare Fig. 4A and B).

We believe that the extension of six amino acid residues influenced the folding of the protein in the cells and prevented the correct association of monomeres into an active tertameric holoenzyme.

As the protein fold is a description based on the secondary structure, the formation of secondary structure in sequence influences the folding of protein.

The SNPs observed among TaSTOP1 homoeologues showed minor changes in respective amino acids of putative proteins which could alter the secondary structures by influencing the folding of these proteins (Additional file 1).