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Modulation of these trafficking proteins is generally thought to influence synaptic plasticity.
However, recent work suggests that the movement of molecules and organelles between the spine and the adjacent dendritic shaft can critically influence synaptic plasticity.
In the brain, EGF family members act as neurotrophic molecules, serving to enhance stem cell proliferation and neural differentiation, and they also influence synaptic plasticity [7], [8], [9].
It is likely that the developmental excitation of high-affinity nicotinic receptors by endogenous acetylcholine during this period of development would influence synaptic plasticity, as has recently been shown with excitation of nicotinic receptors in prefrontal interneurons [46].
Pro-inflammatory interleukins influence synaptic plasticity, neurogenesis and neuromodulation [ 69].
Specifically, we examined whether dopamine D1/D5 receptors influence synaptic plasticity in the hippocampus that is facilitated by novel spatial exploration and LC stimulation.
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However, recent work suggests that the movement of molecules and organelles between the spine and other neuronal compartments, such as the adjacent dendritic shaft, influences synaptic plasticity.
This served as a control experiment to evaluate if the reward itself influenced synaptic plasticity.
This influences synaptic plasticity, for instance through alteration of long-term potentiation (Wigstrom and Gustafsson, 1983).
These data indicate that rats perceive 2D space and that this information influences synaptic plasticity processes in the hippocampus.
This demonstrates not only that passive learning influences synaptic plasticity but also that "2D" spatial imagery has a significant impact on synaptic plasticity.
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