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It appears that preleukemic clones can persist during childhood and that only a minority progress to leukemia, suggesting that postnatal exposures could influence progression (Maia et al. 2004).
NAFLD is considered a complex disease trait such that interactions between the environment and a susceptible polygenic host background determine disease phenotype and influence progression.
During this second year I have been granted I am focused in exploring how such changes following Kras alterations influence progression to carcinoma, dictate the degree and type of immune cell involvement in these tumors, and mediate the efficacy of immune checkpoint inhibitors.
A report on the study, believed to be the first to show that the patient-caregiver relationship may directly influence progression of Alzheimer's disease, is published in the September Journals of Gerontology Series B: Psychological Sciences and Social Sciences and currently available online.
Thus, the absence of MMP13 did not influence progression in the primary tumors.
This is particularly relevant for PSC, where no medical treatment has yet been shown to influence progression to liver cirrhosis and liver transplantation [51].
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To study the growth rate and factors influencing progression of small infrarenal abdominal aortic aneurysms (AAA).
In a prostate cancer model, AR Q tract length influences progression and castration response.
The pretreatment neutrophil-to-lymphocyte ratio (NLR) has been associated with cancer prognosis, influencing progression and chemosensitivity.
To date, the function of C16orf74 is unknown, and additional studies are needed to define the precise pathway by which C16orf74 influences progression in primary NMIBC.
ISRCTN: ISRCTN79355192 Distinguishing between metabolic disturbances in obese non-diabetic patients and type 2 diabetic patients provides information on how obesity related risk factors-including dyslipidemia, hyperglycemia, and hyperuricaemia-influence progression to type 2 diabetes.
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