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Thirdly, it is important to explore the influence of developmental factors on the outcomes of developmentally appropriate CBTs for adolescents.
Knowledge on the influence of developmental changes on drug pharmacokinetics (PK) and pharmacodynamics is limited.
In addition, clear evidence of the influence of developmental factors (fruit maturity) on FD and other variables was also recorded.
The influence of developmental changes in childhood can be explored primarily by using size and/or age as covariates.
In population models, the net influence of developmental changes in underlying physiological processes on drug clearance is quantified in covariate models.
Finally, we need to consider if we are fully aware of the influence of developmental aspects affecting children's competence, and if this makes children's competence different from adults.
Similar(42)
Furthermore, one of the future goals may be to explore the possibilities of cross-validation of the models, in which the reported influences of developmental changes on a certain PK or PD parameter of one drug are evaluated for use in another drug that goes through the same metabolic route or shares the same mechanism of action.
We consider theoretical, methodological, and artifactual factors that influence characterization of developmental and adaptive changes in childhood.
These data indicate that both enhancers are regulated independently and are active under the influence of distinct developmental pathways.
We evaluated the influence of early developmental exposure to PBDE-47 on the female reproductive system.
However, the influence of the developmental statuses of individual countries, as defined by the United Nations Development Programme's Human Development Index (HDI), on these factors has not been previously studied.
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