Sentence examples for influence gene activity from inspiring English sources
Some of these DNA bases serve as landing spots for proteins that influence gene activity.
Beyond defining proteins, the DNA bases highlighted by ENCODE specify landing spots for proteins that influence gene activity, strands of RNA with myriad roles, or simply places where chemical modifications serve to silence stretches of our chromosomes.
Such complex interactions are ubiquitous in biological processes: enzymes act on the production rate of metabolites, information is passed on from one layer of neurons to the next, transcription factors form complexes which influence gene activity etc.
Thus, "Unraveling the rules and factors that determine how nucleosomes are positioned and how they influence gene activity and evolution is one of the central questions in biology today".
Our findings suggest that non-coding regions such as minisatellite repeat regions may influence gene activity.
First, methylation of CpG dinucleotides within transcription-factor binding sites can inhibit transcription-factor binding and, therefore, directly influence gene activity.
Nucleosome organization influences gene activity by controlling DNA accessibility to transcription machinery.
doi: 10.1038/sj.bjc.6600372 www.bjcancer.com © 2002 Cancer Research UK Epigenetics is defined as an inheritable effect that influences gene activity but does not involved a change in the DNA sequence.
Ultimately we would like to have a more complete understanding of how the 3D organization of these cis-elements specifically influences gene activity and what gene products and mechanisms underlie the formation of these clusters.
Although they represent only one of numerous mechanisms influencing gene activities, miRNAs specific to the maturation stage could be involved in regulating several key processes of enamel maturation by influencing mRNA stability and translation.
It seems likely that other uncharacterized enhancer bearing sub-nuclear domains occupy these 'dark' territories and influence local gene activity not detected by our current assays.
