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We also identified an inflated frequency of SNPs at the G base of the canonical AG acceptor site which has been previously identified as a sequencing artifact [ 48].
Although the ATL1 A allele has inflated frequency in Caucasians compared to African Americans, this is substantially influenced by allele A co occurring with the very common 7 3 4+haplotype (microsatellite haplogroup A).
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We did not consider the a posteriori power estimation option in mitPower under the assumption that estimates would be strongly affected by the fact that population stratification has severely inflated frequencies in cases versus controls in the different cohorts reviewed (see Results below).
Recent analyses of artificially constructed communities with known diversity and structure indicate that existing methods may systematically lead to inflated low frequency counts.
LR102 produces an accurate if slightly inflated measures of cough frequency.
The power spectral density of thin films on LaAlO3 and SrTiO3 substrates exhibits an inflated shape at a spatial frequency into 10 μm−1 range with uniformly formed small grains, while LaNiO3 on sapphire showed a high root mean square roughness.
b) Zero-inflated Poisson (ZIP) model, which will explain the mean attack frequency and the zero-inflation probability (i.e. assuming an excess of zero observations).
For example, as previously discussed, misspecification of allele frequencies can lead to inflated type 1 errors for the Sun et al. [2002] method.
For rare diseases with low infection rates, the observed counts typically contain a high frequency of zeros (zero-inflated), but the counts can also be very large (overdispersed) during an outbreak period (1).
Although in our simulations under multiplicative models the method proposed by Sun et al. [2002] tended to be most powerful, it can lead to highly inflated type 1 errors when allele frequencies are misspecified.
Due to the high frequency of zeros, a zero-inflated model was considered.
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