Sentence examples for inflammatory signalling from inspiring English sources

The TLR genes remain strong candidates for susceptibility genes in RA given their crucial role in mediating inflammatory signalling.

We conclude that CFTR modulates downstream signalling (perhaps from TNF-R1) and suggest that CFTR controls release of inflammatory molecules, resulting in suppression of inflammatory signalling.

The most important, however, involves intracellular inflammatory signalling.

IRP1−/− mice also mount an efficient inflammatory signalling response to turpentine [ 190] and do not exhibit differential sensitivity to anthracycline-induced cardiotoxicity compared with wild-type animals [ 191].

For example, the induction of the enzyme by IL-1 and TNF-α may be part of an autocrine feedback mechanism regulating inflammatory signalling.

In addition to feedback regulation at the level of transcription, microRNAs have recently been identified that serve in post-transcriptional negative feedback loops that modulate inflammatory signalling.

Extracellular ATP is a cytotoxic, pro-inflammatory signalling molecule whereas its product adenosine constitutes a universal and potent immune suppressor.

The upregulation of anti-inflammatory signalling coincides with the upregulation of angiogenic factors in the bone haematoma (Schmidt-Bleek et al. 2012a; Schmidt-Bleek et al. 2015).

The haematoma matures over the healing period and already after 24 h the anti-inflammatory signalling increases, to end the pro-inflammatory burst (Schmidt-Bleek et al. 2012b).

Since during physiological healing, after only 24 h the anti-inflammatory signalling increases, terminating the pro-inflammatory burst (Schmidt-Bleek et al. 2012b), this new inflammatory impulse could be equalized to a prolonged inflammation phase.

In addition, AMPK activation attenuates pro-inflammatory signalling and monocyte adhesion to the endothelium [ 20].