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Combined with many researchers' study, we infer that polygala saponins cannot cause gastrointestinal ulcer by producing inflammatory irritation.
Tenosynovitis is characterized as an inflammatory irritation of the tendon sheath synovium resulting in an abnormal increase in the fluid surrounding the tendon [ 62].
The hard-palate, soft palate, buccal mucosa, tongue, and gingiva were examined for abnormalities, including inflammation, ulceration or other signs of inflammatory irritation that might be expected to be secondary to exposure to CHX.
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A non inflammatory chemical irritation of the neural tissue associated with tendons has been proposed as a potential mechanism of pain production [ 5, 17, 18, 24, 27, 28].
The jet-lagged mice also mounted a stronger inflammatory response to irritation by an experimental chemical a test used to gauge immune-system sensitivity that hints the animals may be more prone to inflammatory disease.
This results in inflammatory changes and irritation of pain receptors.
Inflammatory reactions including eye irritation, respiratory infections, wheeze, bronchitis, and asthma in workers in water-damaged or "moldy" buildings have been associated with the presence of high numbers of microorganisms (8 ).
Use anti-inflammatories to decrease irritation.
Often mistaken for tendonitis, superficial irritation or inflammatory arthritis, the proper diagnosis of this condition, Haglund's syndrome, is essential in order to ensure that patients receive the appropriate treatment.
Short-term exposures can cause irritation and inflammatory symptoms of transient nature.
Its removal prevents the resulting irritation and inflammatory response when removing the unwanted additional free lipid from within a recipient site.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com