Sentence examples for inflammatory feedback from inspiring English sources

In a recent study, we found that PTEN inactivation in HER2-positive breast cancer cells activates an IL-6, STAT3, AKT and NF-κB involved inflammatory feedback loop, which expands EMT type of breast CSCs [87].

These additional complexities to the inflammatory feedback loop are likely to contribute to the epigenetic switch.

These observations uncover additional complexities to the inflammatory feedback loop that are likely to contribute to the epigenetic switch.

These data imply that an inflammatory feedback mechanism may sustain the deregulation of HNF1α in the impaired hepatocytes.

CSCs are therefore likely to exhibit increased dependence on the inflammatory feedback loop, and pharmacological interference with this pathway may limit their tumorigenic potential.

Hence, there is additional complexity to the inflammatory feedback loop that involves STAT3 transcriptionally upregulating NF-κB and IL6, both of which activate STAT3.

Our results are consistent with the notion that MIF up-regulates TLR4 expression and that TLR4 stimulation in turn leads to the production of MIF, thus establishing a mutually-reinforcing, pro-inflammatory feedback mechanism [29].

In murine mature macrophages, Twist1 2 are also implicated in an anti-inflammatory feedback loop triggered by IFNα to counteract production of TNFα.

GC plays an important role in the regulation of glucose metabolism and is part of the anti-inflammatory feedback mechanisms of the immune system.

Since STAT3 is highly tyrosine phosphorylated in UC and CD patients [ 33], the upregulation of SOCS3 represents an anti-inflammatory feedback loop.

By inhibiting the expression of IRAK and TRAF6, the expression of miR-146a/b creanes anti-inflammatoryory feedback loop, inhibiting NF-κB induced proinflammatory cytokine production [ 86].