It has been suggested that when the immune response maintained by IL-23 persists in an uncontrolled manner, this protein may switch from being an integral part of the host defense to being a pro-inflammatory contributor to autoimmune disease.
Using VEGF stained sections we demonstrated both carcinoma and host inflammatory cells as contributors of VEGF to the tissues.
Many researchers are investigating the expression of inflammatory proteins as contributors to the variable onset and progression of infection, sepsis, and organ dysfunction.
In this review, we show how these approaches have revealed an uncontrolled inflammatory response as a contributor to the extreme virulence of the 1918 pandemic and avian H5N1 viruses, and how this response differs from that induced by the 2009 H1N1 viruses responsible for the most recent influenza pandemic.
ISG15 is a stress-response gene that may function as a tumor suppressor and contributor to inflammatory responses [ 30].
Experimentally-induced endotoxic shock demonstrated that the liver is a major contributor of inflammatory cytokines in the bloodstream [ 14].
Senescence-like neurons might be a source of oxidative and inflammatory stress and a contributor to brain aging.
14 Improved immune function plays a critical role in regulating the inflammatory process, a primary contributor to chronic disease.
These data further establish the role of adipose tissue as a contributor to inflammatory response in CD and provide a rationale for targeting mesenteric fat in the treatment of this chronic disorder.
As the principal cellular component of the inflammatory host defense and contributor to host injury after severe physiologic insult, the neutrophil is inherently coupled to patient outcome in both health and disease.
A variety of prostanoid cyclo-oxygenase (COX) enzyme products (prostaglandin (PG E2, PGD2, PGF2α, thromboxane, PGI2) are made during inflammation, but PGE2 is considered to be the major contributor to inflammatory pain.
