Sentence examples for inflammatory complex from inspiring English sources
Cytokines, free radicals, prostaglandins and growth factors are a part of the activated inflammatory complex.
The present study investigates the influence of all SEPS1 variants previously correlated with increased pro-inflammatory cytokines levels (polymorphisms at -105G/A, 3705G/A and 5227C/T) and of the SEPS1 haplotypes on predisposition to inflammatory complex diseases.
The binding of TNF to TNF-R1 causes recruitment of several intracellular adaptor proteins leading to downstream signaling events that activate the inflammatory (complex I) and apoptotic (complex II) processes.
The human genome reveals more than 80 DD superfamily members, implicated primarily in the assembly of apoptotic and inflammatory complexes.
HMGB1 can form highly inflammatory complexes with CpG DNA [ 15, 16] and IL-1β [ 17], suggesting that HMGB1 is necessary but not sufficient to induce inflammation [ 18].
Members of the death domain superfamily are involved in the assembly and activation of apoptotic and inflammatory complexes through homotypic protein-protein interactions [ 13].
In addition, Syk can also motivate the NLRP3 inflammatory complexes under the action of ROS generated by ERK, cause the activation of Caspase-1, and change the ProIL-1β into the activated form, IL-1β [ 9, 35, 36].
The name was coined in 1999, when the group of Seymour Klebanoff isolated a pro-inflammatory complex, containing at least three peptides, from the phenol-soluble fraction of Staphylococcus epidermidis culture filtrate.
Our data suggest that non-toxic brominated noscapine analogs perhaps inhibit the pro-inflammatory responses by inducing autophagy that dampens inflammation by attenuating or recycling the inflammatory signaling complex.
b, As the disease progresses, cells are damaged and release products that can trigger formation in microglia of a pro-inflammatory protein complex called the inflammasome.
For many complex inflammatory diseases, polymorphisms in inflammatory genes are more likely to act as modifiers for disease susceptibility rather than sole determinants.
