Sentence examples for inflammatory background from inspiring English sources

In the lymph node, PTCL-NOS shows paracortical or diffuse infiltrates with effacement of the normal architecture, with a broad cytological spectrum and a frequently observed inflammatory background.

The findings are those of a very unusual histiocytoid proliferation with bizarre large multinucleated cells of which many exhibit emperipolesis in a characteristic highly inflammatory background composed of lymphocytes and plasma cells in a variable sclerotic and somewhat myxomatous matrix.

Idiosyncratic drug hepatotoxicity represents a major problem in drug development due to inadequacy of current preclinical screening assays, but recently established rodent models utilizing bacterial LPS co-administration to induce an inflammatory background have successfully reproduced idiosyncratic hepatotoxicity signatures for certain drugs.

However, despite a common inflammatory background, we did not observe a similar lipid profile between sepsis and trauma patients.

Chronic disorders of an inflammatory background, such as COPD and asthma, often overlapping, diagnostically and therapeutically misguided and always difficult to manage, are in focus due to an increasing prevalence across the age range.

It has already been suggested that the excess of TP53 transitions at CpGs found in cancers arising on a chronic inflammatory background, such as CRC in ulcerative colitis and bladder cancer associated with Schistosomiasis, results from nitrosative stress [74], [88].

This is contradictory to the postulate that an anti-inflammatory background could predispose to invasive candidiasis in ICU patients and exhibiting a "Post-infectious immune suppression conditions".

We suggest that IL-1b enhances the inflammatory response of TNRSF1A mutated cells due to their hyper-inflammatory background.

Early evidence suggests that anti-IL-1 drugs such as Anakinra provide encouraging prognoses in patients with TRAPS, suggesting that IL-1 might also serve to amplify the pro-inflammatory background in TRAPS patients.

Notably, miR-126-3p miR-126-3p miR-126-3pexpressionted, seemsfically, down-regulatod, in various age-related disorders, suggesting that the compensatory mechanisms enacted be senescent/deregulatednal cellspecificallyluntedown-regulateded condinions sharing an unbalanced pro-inflammatory background [ 53].

These differences in KIR haplotype effects may be important in explaining the longevity phenotype with the increased number of NK and NKT-related cells found in nonagenarians (McNerlan et al. 1998; Peralbo et al. 2007) or conversely with the pro-inflammatory background found with increasing age or inflamm-ageing (Franceschi et al. 2000).