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The inferred point mutational spectrum was restricted to intergenic regions, excluding all DIMs located within RefSeq transcripts.
The above finding that Thg1 is specifically related to the GGDEF and CRISPR polymerases raises interesting evolutionary and functional issues in light of its inferred point of origin.
We used a bifurcation in both the Acacia and thrips clades that is an inferred point of parallel diversification, and therefore temporarily concordant, to estimate the relative timing between clades.
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Our inferred point-mutation rate is intermediate to other previous estimates based on experimental (Drake 1991) and comparative methods (Ochman et al. 1999).
Even if we were to disregard this inferred data point, our observation is also supported by the (admittedly few) sets containing three saccades (cyan, blue and magenta lines).
The inferred joint point responsible for peptide removal from MAT a2 in Z. sapae laid on X region and went through an imperfect tandem sequence (CAAGCA/C 3 at the nucleotide position 653.
The contingent method revealed that mean willingness to pay ranges from 31to4343 €/year/respondent, whereas the inferred method pointed to a slightly higher range of willingness to pay, from 37€ to 44 €/year/respondent.
For example, identification of the recombination events underlying a major switch in substrate specificity during evolution of a bacterial non-ribosomal peptide synthase, allowed Crüsemann et al. [ 36 ] to create enzyme variants that accepted alternative substrates, based on the inferred recombination points.
We believe that the inferred dataset of point mutations may be a valuable complement to SNPs for the analysis of human genetic variation.
Phylogenetic/bioinformatics analysis of the inferred host Acd1 point to a significantly streamlined genome compared to other members of the Sulfolobales.
We then analyzed the patterns in which these disease genes emerged within the Metazoa using phylostratification, a process by which genes are placed into major taxonomic groups ("phylostrata") according to their inferred evolutionary emergence point [ 42].
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