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This allows drug exposure data to be aggregated based on ingredients to create drug eras, which can be described as an inferred period of continuous exposure to a certain ingredient over a certain period of time with a 30-day persistence window (duration allowed between subsequent drug records) [ 12].
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It is important to mention that these inferred periods of extinction are congruent with fossil data also indicating significant extinctions for the clade.
Genes were categorised into four groups based on their presence/absence in different taxa (and hence on the inferred time period when the genes were transferred).
Finally, an inferred insertion period of Merrow, Garfield, and Conan postdated the radiation of two species where these transposons resided (supplementary fig. S5, Supplementary Material online).
Given that more than 250 species of scleractinian corals are supported at the island, it would be interesting and useful to extend these initial studies to additional species at other times of the year, and to confirm inferred spawning period and synchrony with field observations.
Posaconazole was slower acting, but by the conclusion of the treatment period the inferred parasite load had also dropped to background levels.
The timing of movement of this clade from Asia into Africa was likely facilitated by climate and habitat changes that resulted in an increase in grasses (i.e., more open habitats) in east Africa from 9-5 Ma [see [ 25, 26]], and an inferred movement during this period is consistent with Eurasian to African dispersals by other arid-adapted birds [e.g., [ 16, 35]].
In the Late Pleistocene to Recent P/Al (inferred nutrient availability), percent calcium carbonate (%CaCO3) and Ba/Al (inferred productivity) varied regularly at a period of 40 000 years with these factors lagging minimum global ice volumes (interglacials).
Figure 30: Paleogeographic map of the continents during the Late Carboniferous and Early Permian periods showing the inferred distribution of continental ice sheets.
When averaged in a 140 km wide corridor around the modern arc, phase velocities systematically increase from south to north at all periods by 0.15 0.2 km/s, a variation that strongly correlates with heat flow and inferred magmatic heat input (Fig. 4a).
66 67°N) apatite fission track data and models suggest two separate periods of slow cooling: prior to c. 200 Ma and between c. 160 Ma and the late Cenozoic (more recently than c. 20 Ma), each of which was followed by a period of rapid cooling and inferred exhumation.
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