20 Sensitivity assessments omitting inferred task limitations yielded almost identical results.
The same conclusion could be inferred from limited proteolysis studies.
Comparison with emission factors obtained by the lead-tracer method allows us to test the reasonableness of ignoring the limitations of the inferred ventilation method using BaP as a tracer.
Yet there is an inherent limitation with such an approach as inferred models tends to 'over-fit' data [18].
This analytical strategy is useful but has limitations for which solutions remain elusive; the inferred tree can accumulate systematic errors due to the use of concatenated information.
In terms of the choice of the number of inferred states, we have added the paragraph beginning: "A limitation of the proposed technique is that HMM inference requires an a priori specification of the number of states, K. Bayesian inference techniques provide a means to test model order selection, by providing an approximation to the free energy".
A limitation of the OTU approach is that inferred groups for a fixed identity threshold will be different based on the choice of marker due to LGT or rate variation, potentially leading to different conclusions (Brousseau et al., 2001; Schellenberg et al., 2009).
Despite some interesting insights into the inferred genome organization that were raised during this investigation, our approach still faces analytical challenges and limitations.
This inconsistency may at least partly reflect limitations in the exposure assessment, because many of the previous studies, case control studies in particular, inferred workplace exposure to TCE based on occupational title or through the use of job-exposure matrices (Scott and Chiu 2006).
A serious limitation of these epidemiological studies is that, most often, postprandial hyperglycemia was not directly measured, but rather inferred by evaluating glycemia after an oral glucose load with 75 g glucose as recommended by international standards [ 1].
It is the inferred cost difference between those two scenarios.
