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All these cases were assigned repair by inferred assignment in the same exercise.
An inferred assignment of repair was made 254 times, and progression was assigned 143 times, which gives us the prior probability of repair (64%).
The inferred assignment is considered the gold standard.
In the single joint experiment, these figures for inferred assignment were 77% and 58%, respectively.
For each reader we compared the direct assignment of repair with the inferred assignment, using the inferred assignment as the gold standard because this only involves one decision about better/worse.
Judgement of the whole hand assignment of progression or repair was compared with the single joint inferred assignment of progression or repair.
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Dashed black edges represent inferred assignments that match the encoded assignments.
Implicitly, this finding also underscores that there are no typical features regularly recognized by all readers pointing to repair, confirming what was shown in Exercise I. Offering the entire hand or foot resulted in an agreement (≥ 5/7 readers agreed) on an inferred progression/repair assignment in 53/64 888%) patients.
The higher resolution of this structure (2.8 Å vs 3.35 Å) enables confirmation of the inferred stereochemical assignments at stereocenters of GE and enables identification of additional water-mediated H-bonds, including additional water-mediated H-bonds in the network of water-mediated interactions connecting GE to Mg2+(I).
Additionally, electronically-inferred GO assignments of the Citrus probesets using the Blast2GO pipelines [ 62] were downloaded from AgriGO download centre (http://bioinfo.cau.edu.cn/agriGO/download.php) prior to GO enrichment analysis in BinGO [ 58].
The mean (standard deviation) κ value, computed across all possible reader-pairs, was 0.52 (0.10) for the inferred progression/repair/no change assignment, based on a better/worse decision.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com