Sentence examples for inference of linkage from inspiring English sources

The theoretical basis of genome-wide association studies (GWAS) is statistical inference of linkage disequilibrium (LD) between any polymorphic marker and a putative disease locus.

The theoretical kernel of these genetic association studies is statistical inference of linkage disequilibrium (LD) between a tested polymorphic marker locus and a putative trait locus in the population of interest.

More important than the absolute values for inference of Z-linkage is the ratio of mean male to mean female concentration: E (ZZconc/ZWconc).

Morgan's inference was that the degree of linkage depends on physical distance between the genes in the chromosome: the closer the genes, the tighter the linkage and vice versa.

Our second objective was to develop an expansive set of SNPs that can be used for more robust inferences of population structure, construction of linkage maps, and genomic scans of selection.

The inclusion of linkage in the inference accounts for changes in the mutant allele's effective fitness caused by changes in the background population.

Comparative mapping with Chinook salmon permitted inference of the structure of coho linkage groups.

The molecular inference of Ne based on the linkage disequilibrium method for the 2008 2009 sample was Ne =161 (100–296).

The network mining showed advantages on both the construction of the disease network and the inference of molecular mechanisms underlying the linkage between diseases.

Thus, inferences about biological pathways or further support of linkage regions based on most of these data should be avoided, with the exception perhaps of results from GWAS.

It is not clear whether the reports of high temporal precision with full-field flicker provide a solid base for inferences about linkage of discrete, spatially separated stimuli.