Sentence examples for infer functionality from inspiring English sources

In this paper, we used evidence of natural selection to infer functionality of an intronic region implicated in prostate cancer [7].

For example, Thomas et al. (2003) specifically use conserved regions of coding sequence to infer functionality.

Yet, since the joint contribution of multiple 'doses' is likely to determine transcriptional outcomes, it may be difficult to infer functionality of a given TFBS in isolation from others.

First, the short lengths of the identified ORFs and their general lack of detectable homology or reading-frame conservation with related species make it difficult to infer functionality [ 37, 38].

Although this does not directly infer functionality, the majority of these twenty genes has been lost in the obligate endosymbionts of the mealybug, and some of these nuclear encoded genes complement the genes retained in the endosymbionts leading to complete pathways.

Although Gene Ontology has its limitations as it is biased towards what is already known, it is still a universal key tool for functional annotation inferring functionality based on sequence identity, domains and structure, and literature studies.

The binding interactions of sVEGFR1, in particular, were inferred functionalities based on the first six Ig-like domains that it has in common with VEGFR1 (Fig. 1D).

The few identified highly expressed non-conserved putative miRNA tend to originate within repeated regions, making it difficult to infer their functionality.

Accurate predictions of homology relationships can be used to infer gene functionality [ 22], reconstruct species phylogenies, and characterize genomes based on their encoded genes [ 19].

The combination of information from all organisms in one central repository makes it possible to integrate knowledge from different databases and to infer the functionality of newly discovered genes.

While inferring hippocampal functionality in the infant through cognitive testing and inference alone may have been appropriate three decades ago (when Schacter and Moscovitch, 1984, proposed their model), surely in this era of advanced, non-invasive neuroimaging techniques we should be attempting to ask more sophisticated and potentially more useful questions of this developing system.