Sentence examples for infectivity and replication from inspiring English sources

To confirm the cell specificity, we carried out cell culture infection experiments by comparing viral infectivity and replication in GI-101A tumor cells and in endothelial cells.

We speculate that virus may employ either strategy (to usurp cvhRNA networks or to avoid miRNA targeting) for the establishment of persistent infection, depending on which strategy plays a major role in favoring viral infectivity and replication.

Due to poor adenoviral infectivity and replication in mouse tumor cell types compared with human tumor cell types, use of human-type adenoviral vectors in mouse animal model systems was limited.

Tumor tissue slices offer a stringent model system for preclinical evaluation of adenovirus therapies, since the slices retain a morphology and phenotype that more closely resembles the in vivo setting than cell line cultures, and this system has been shown to have utility in the evaluation of viral infectivity and replication.

The correlation of interferon expression with infectivity and replication kinetics for different viruses is yet to be determined.

Based on specific infectivity and replication data, the chimeric virus 41855/LR-GFP-226V was not attenuated in BHK-21 cells (supplemental data Table S1), indicating that this genome region is interchangeable between the LR2006 OPY1 and Ag41855 strains.

The SH3 binding motif of Nef was partially required for infectivity enhancement and replication but not for receptor downmodulation.

Here, we demonstrate enhanced infectivity and productive replication of adenovirus in mouse melanoma cells following introduction of both the Coxsackievirus and adenovirus receptor (CAR) and E1B-55K genes.

Analysis of viral infectivity and DNA replication with BSCTV and C4 deficient BSCTV mutants revealed that BSCTV C4 is essential for disease symptom formation, but not required for viral DNA replication.

Moreover, since Ad5/FC31.1 and Ad5/FC31.2 vectors are identical (except for an extra 65-bp spacer between attB and ψ in Ad5/FC31.2) and have a similarly delayed viral life cycle (Reference 8, Figure 3), as well as similar viral infectivity and DNA replication, they were used interchangeably throughout the experiments.

Infectivity and viral replication were assayed, and cytokine responses were determined by Cytometric Bead Array(CBA) analysis.