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To determine the relevance of these in vitro findings, we performed survival studies between the two backgrounds in a purely infectious model of peritonitis.
In addition, we studied the impact of PrPRES on calcium homeostasis using an acute PrD infectious model where exogenous PrPRES was added to the cells at nanomolar concentrations.
In this study we evaluated the MEA for its use in DNA vaccination using Hepatitis B virus as the infectious model.
On the other hand, a clinical strain of Burkholderia cenocepacia isolated from a CF patient was used to show that the intraperitoneal administration of bacteriophages was more effective than intranasal applications in a non-deadly infectious model [17].
Consequently, 100 and 200 mg/kg were used to ascertain efficacy in the infectious model.
For this study crude, a crude acetone extract of L. alata leaves was evaluated for its acute toxicity in a healthy chicken model and for efficacy in an infectious model of aspergillosis (A. fumigatus).
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So for this reason, infectious models with impulsive vaccination are concerned by more and more scholars.
Our results emphasize that reliability of infectious models critically depend upon genetics of the host.
The finding of a sensitizing role for exogenous IFN, while surprising, has been described in other infectious models.
In other infectious models, IL-22 induces the secretion of anti-microbial peptides and protects tissues from damage by preventing apoptosis.
IL-22 is induced during certain infectious models including Salmonella enterica [14], Toxoplasma gondii [36], Citrobacter rodentium [13], Klebsiella pneumoniae [26], and in an induced model of colitis [37].
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