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Establishing the MOI of P.falciparum samples using sequence data will assist with understanding the dynamics of infections, pathogenesis, effect of transmission intensity, drug efficacy and parasite genetics.
It is an epidemiological measure that can improve the understanding of many areas of parasitology, including the dynamics of infections, pathogenesis, effect of transmission intensity, drug efficacy and parasite genetics (Ross et al., 2012).
Several studies strongly support the hypothesis that colonization of the aerodigestive tract is primarily involved in VAP and other ICU-acquired infections' pathogenesis, since micro-organisms move into the lower respiratory tract or, through the gut, into the blood or regional lymphatics [ 16- 22].
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Epidemiological studies of HPV persistence suffer with several challenges in definitions, study designs, and analyses that undermine its importance in identifying and understanding the interactions between the viral and host genomes in the process of HPV infection pathogenesis.
These results demonstrate the potential for CWD prion transmission via urine and/or feces, and highlight the application of more sensitive assays such as sPMCA in identification of CWD infection, pathogenesis, and prevalence.
Overrepresentation of CC17 clone among invasive neonatal strains is now well recognized worldwide [9]-[13], and highlights the fact that this clone is well adapted to neonate infection pathogenesis and may possess specific virulence traits that enhance CNS invasiveness in this population [14], [26].
Genes unique to L. santarosai are likely to be necessary for aiding infection (pathogenesis).
However, overall changes occurred in JEV have increased the infection, pathogenesis and mortality rate.
The model (fig 1) consisted of differential equations that described tuberculosis infection, pathogenesis, and mortality among populations older than 15 years (web appendix).
Results of these studies should be cautiously extended to humans due to the primary impact of host-specificity on the infection pathogenesis [ 10, 11].
Insight into host-pathogen interaction dynamics is not only essential for the understanding of infection pathogenesis, but also for development of therapeutic interventions for controlling infectious diseases.
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