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These findings suggest that these hierarchical 3D multidrug scaffolds are promising candidates as platforms for local bone infection therapy.
These findings suggested that the proposed surface functionalization strategy provided MBG materials with notable antibacterial adhesion properties, hence making these materials promising candidates for local bone infection therapy.
There was no statistically significant difference in mortality rate according to infection therapy appropriateness (36/157, 23%% vs 15/45, 33%%, respectively, for appropriate and inappropriate therapy p = 0.166).
Since the eradication of endopathogenic microbiota is a major goal in endodontic infection therapy, photo-activated disinfection (PAD) can be used as an alternative therapeutic method in endodontic treatment.
Therefore, the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE-IT TIMI 22) trial has been designed specifically to determine whether standard LDL-C reduction (with pravastatin 40 mg) provides a similar clinical benefit to more aggressive LDL-C reduction (with atorvastatin 80 mg).
There was no failure of infection therapy.
Similar(38)
These positive results open up very promising expectations for their potential application in new infection therapies.
Hence, the stability of the end-tagged peptides, notably KNK10-WWWWW, against a range of proteases, combined with potent bactericidal effects, could make this peptide a potential candidate for skin infection therapies.
In a subanalysis of the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22 (PROVE-IT TIMI 22) trial to assess the impact of low on-treatment TG on CHD risk beyond LDL-C < 70 mg/dL, Miller et al. [ 15] demonstrated that on-treatment TG below 150 mg/dL was independently associated with a lower risk of recurrent CHD events.
Fortunately due to concerns regarding resistance, the 2010 Infectious Disease Society of America IDSAA) guideline for uncomplicated cystitis now recommends fluoroquinolone antibiotics as alternative agents only when other urinary tract infection therapies cannot be used [ 15].
Serum procalcitonin (PCT) concentration is used to guide antibiotic decisions in choice, timing, and duration of anti-infection therapy to avoid antibiotic overuse.
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