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We also were able to identify 34 patients who had both an MRSA infection isolate available for testing and a MRSA isolate from recent admission screening.
In comparison, CC5-associated spa types made up more than nearly 70% of colonization isolates, yet accounted for a similar percent of infection isolates as ST8 (i.e., there was 1 infection isolate to every 4 colonization isolates).
Compared to previous MRSA clone studies in Taiwan, which showed only four major infection isolate clones (ST239, ST59, ST241 and ST5) [ 22, 23], our study revealed more heterogeneous MSSA lineages.
Specifically, CC8-associated spa types made up only 13% of colonization isolates, yet they made up more than 30% of infection isolates (i.e., a ratio of 1 infection isolate to every colonization isolate).
Sample pairs where an infection isolate was collected within 30 days of a screening swab from the same patient were included in the analysis.
Additional details regarding the birds involved in this study, infection isolate and methodologies applied to produce clones are summarized in Table 1.
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A single infection (isolated) was relatively uncommon (22.6%) among the HIV infected patients, but common among the malaria, hookworm and bacteraemia infected patients, in whom 60.0, 52.2 and 37.1% were isolated infection, respectively (table 4).
Here, haplotypes were derived from genotypes of single clone infection isolates (excluding any isolates with mixed alleles detected).
Infection isolates grew faster than carriage isolates.
The major PFGE cluster of MSSA infection isolates included ST1, ST6, ST7, ST12, ST188, and ST97.
SHV-12 was also found among bloodstream infection isolates from children within the same hospital [ 12].
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