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The down-regulation of the anti-apoptotic miRNAs (novel_16, novel_100, novel_84, novel_92 and novel_50) reinforces the importance of investigating the apoptotic signaling cascade upon Wolbachia infection (Additional file 3: Table S3 and Additional file 4: Table S4).

Scanning electron microscopy (SEM) revealed the presence of membrane ruffling on both mock-and virus-infected PMΦ cells, with increased membrane ruffling following virus infection (Additional file 2: Figure S2A).

However, no significant phenotypic differences were observed in the aerial parts of cultivated and wild rice varieties with or without M. oryzae infection (Additional file 1: Figure S1).

In all three time-course experiments tested, the nematode genes transcript levels increased in root samples all along infection (Additional file 1: Table S1).

Further, expression analysis of all rice MAPKKs in Massively Parallel Signature Sequencing (MPSS) (Brenner et al. 2000) database revealed the increase in expression levels of OsMKK6 and OsMKK10-2 in different libraries post M. oryzae infection (Additional file 3: Figure S3).

We did not observe an independent association between the storage time (RBC units >14 and RBC units >21 days) of RBCs and onset of nosocomial infection (Additional file 2: Table S2).

In addition, the proliferation of LL2 cells was inhibited by LV-Kallistatin infection (Additional file 1).

Relative expression of all genes increased with time during infection (Additional file 1).

Two were highly down-regulated, whereas the other three were up-regulated during early or late infection (Additional file 10).

Stable αv integrin knockdown MCF10A-M4 celinesnes were established by lentiviral shRNA infection (Additional file 3: Figure S3A-D).

All genes used in this work were, to some extent, differentially expressed upon infection (Additional file 4).

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