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For simplicity of model development, it is assumed at first that individuals can be immediately diagnosed as infected upon infection and also that they become immediately infectious upon infection with no latency period and remain infected throughout the epidemic.
We assumed that individuals can be immediately diagnosed as infected upon infection.
For example, a larva infected in August (L8) could grow into an infected nymph (since larvae are infected upon feeding, the next opportunity to infect other individuals does not come until they feed next time as nymphs) and infect larvae in August or September, nymphs between June and September, H1 hosts between June and September, and/or lay infected eggs.
This key definition points to two important host characteristics that control the spread of infection: first, the susceptibility of non-infected individuals, i.e. the propensity of becoming infected upon contact with an infectious individual or substance, and second, the infectiousness of the infected individuals, i.e. the ability of an infected individual to transmit the infection.
Instead, neutrophils become infected upon recruitment to established granulomas, where they phagocytose dead and dying infected macrophages (Yang et al., 2012).
Five children had been adopted from HB-endemic countries and were already infected upon arrival in Canada.
Similar(49)
This is not a formal lower bound, since in the limit of infinite infectiousness within the household, all members of the household will be infected simultaneously upon introduction of the infection into the household.
These studies provide strong evidence on the contribution of defective cellular Jak-STAT signaling in HCV infected hepatocytes upon the interferon antiviral response.
We found that exosomes released from BCG infected macrophages upon intranasal administration of C57Bl/6 mice induced a CD4+ and CD8+ memory T cell response.
However, MHC class II expression did not increase on FMDV infected cells upon TNF-α treatment (Fig. 2B), making this difference statistically significant (p<0.05) as compared with the uninfected MoDCs after adding TNF-α.
Since we employed ethidium homodimer which primarily stains necrotic cells, not living or apoptotic cells, our study monitored the necrosis rate of the HIV-1 infected macrophages upon exposure to the ALP compounds.
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