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Marshall infected himself with Heliobacter pylori bacteria and then treated the infection with antibiotics.
His explanation was that he had accidentally infected himself with a needle at his medical laboratory.
To emphasise their point, in 1985, Dr Marshall deliberately infected himself with the helicobacter pylori bacterium to prove it caused acute gastric illness.
Technology has also made the experiment safer than when Ballou infected himself: The polymerase chain reaction test can detect minute amounts of parasite DNA and identify an infection 2 days earlier than traditional microscopy, and if volunteers receive immediate treatment, they rarely suffer any symptoms.
The outbreak ended before the serum could be used in Africa, but some of it was given later that same year to a researcher in the United Kingdom who accidentally pricked infected himself while transferring blood from a guinea pig infected with Ebola.
In 1985, for example, Marshall underwent gastric biopsy to put evidence that he didn't carry the bacterium, then deliberately infected himself to show that it in fact caused acute gastric illness.
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In 1985, [Dr] Marshall showed by deliberately infecting himself with the bacterium helicobacter pylori that it caused acute gastric illness.
In standard histories Hunter may be an enlightenment hero; in Mantel's reimagining, he is somebody much stranger, stabbing and infecting himself out of intellectual curiosity, twisted and tormented by his thirst for experimental knowledge.
Initially, he thought about writing a play dealing with a doctor who has been working with AIDS patients and intentionally infects himself with the virus in order to understand how they feel.
And it wasn't just unhinged Victorians or deranged Edwardians who inflicted experiments on themselves; Barry Marshall, an Australian physician, won the Nobel prize in 2005 for infecting himself with Helicobacter pylori to prove that this type of bacteria caused stomach ulcers.
Until the two winners identified the bug responsible and showed what it was doing (in Dr Marshall's case by deliberately infecting himself), ulcers were seen as the result of a biochemical error (the production of too much stomach acid), often brought on by stress.
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CEO of Professional Science Editing for Scientists @ prosciediting.com