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The phenotypically female infant was noted to have clitoromegaly at 10 weeks of age.
The infant was noted to have mild pitting oedema of lower limbs, extending up to the umbilicus, which spontaneously resolved by day 3 of life.
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A weak trend of increased representation of homozygous KIR2DL3 in the absence of its' HLA-C ligand (i.e. homozygous C2 group) in the IP infants compared to the EU infants was noted (P = 0.086; OR = 2.87).
By 6 7 months however, 50% infants were noted to be still seropositive.
To our knowledge, this is the first time an increased number of postmature infants is noted in an ALTE population.
Heterogeneity in the qualitative assessment of pain by each trio of adults was noted per infant evaluated.
A trend however was noted in the infant group where IP infants had approximately 20% lower representation of KIR3DL1+Bw480Ile compared to EU infants (P = 0.062; OR = 0.41) (Table S4), however this trend was lost post MVL adjustment (Table 2) and upon NVP stratification (data not shown).
A similar association was noted between infants colonized with multidrug-resistant enterococci (30.5 vs. 35 weeks of gestation, p = 0.0006, Figure 3B).
This finding is similar to other studies where an increased risk of allergic sensitization was noted in infants who received vitamin D supplementation., Likewise, Gale et al. noted that maternal 25(OH D concentrations greater than 75 nmol/L (30 ng/mL) were associated with 5-fold increased odds of asthma at 9 y of age in the exposed children.
A higher risk of mastitis was noted when the infant was separated from the mother for more than 24 h (OR: 4.04).
The infant received routine postnatal care, but was noted to have persistent irritability during the first 12 hours after birth, which was attributed to a caput succedaneum.
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