These models have uncertainties due to inevitable input errors, poorly defined parameters, and inadequate model structures.
Despite of the inevitable input of laboratory animal trials, recent studies have shown that animal pain models have repeatedly failed to predict clinical analgesic efficacy and adverse side effects of potential drug molecules in human pain patients.
Short-term fluctuations in input are inevitable in metabolic systems because inputs of metabolites can change dramatically after each meal.
Comedy partnerships often end in divorce (Martin and Lewis), or at least in conscious uncoupling (Nichols and May), amid the inevitable asymmetries of input, credit, commitment, attention, ambition, and pay.
That, however, sits uncomfortably with the idea that mental decisions are purely the consequence of electrochemical interactions in the brain, since the output of such interactions might be expected to be an inevitable consequence of the input.
If the excitatory input is allowed to have the "foresight" of turning off as soon as the target crosses the firing threshold, i.e., as soon as firing becomes inevitable even without further input, then precise synchrony is indeed optimal, as the commonplace reasoning would suggest.
"But if it's inevitable, that's where the input of the local residents and elected officials comes in".
Input saturation is inevitable in many engineering applications.
This is because there are inevitable timing drifts between the two inputs to the system.
Conventional agriculture can quickly and easily strip soil of its nutrients, which causes a need for fertilizer inputs (on top of the inevitable pesticide inputs).
