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But Clare may have enough in her favour to withstand the inevitable adverse reaction to such exposure.
However, inevitable adverse effects and acquired drug resistance severely constrain the therapeutic outcome.
The use of a physiological carrier to deliver therapeutics throughout the body to both improve their efficacy while minimising inevitable adverse side effects, is an appealing perspective that can be applied in many clinical settings.
Traditional therapies (surgery, chemotherapy, and radiotherapy) are not effective in managing advanced metastatic melanoma and are often accompanied by inevitable adverse effects [4].
(Focus Group 1, Pharmacist 1) While a number of participants acknowledged concerns that learning the risks associated therapy may dissuade patients from accepting treatment, a strong sense of responsibility to prepare their patients for the inevitable adverse effects emerged.
However, if the overriding intention is to obtain the desirable effect (namely, to keep the patient symptom free), then it is considered acceptable to provide such a treatment, even though a predictable harmful and inevitable adverse effect might occur (hastening death); this reasoning is usually referred to as the 'principle of double effect' [ 15].
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"The information provided to the minister identified in sufficiently unambiguous terms the inevitable and considerable adverse effect which the closure of the fund will have, particularly on those who, as a consequence, will lose the ability to live independently," she added.
Further cancellations are inevitable given the adverse weather conditions at other airports around Europe".
"Some adverse impacts are inevitable if the significant benefits of the proposed action are to be realized," said the new version of the impact statement.
There seemed to be a general acceptance that adverse effects were inevitable and therefore not generally recorded in the patient notes; interviewees suggested that the lack of recording was not corticosteroid-specific.
(M2) Most interviewees felt that adverse effects were inevitable and were frequently not identified until they were very obvious, for example Cushingoid syndrome: "It's the long term side effects that are actually important and they are subtle and sneak up on you".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com