Although antisense inhibition of miR expression is an inefficient process, introduction of anti-miR-15a or anti-miR-16 in the MCF-7/Vector and MCF-7/HER2 cell lines resulted in a significant increase in tamoxifen resistance.
However, recent research has shown that the adoption of deployment policies carries the potential of locking in the technology that is most cost-effective at the point of policy introduction, but may be inefficient in the long term.
Because the service was deemed inefficient and unpopular, especially because of the introduction of express mail and priority mail, special delivery was discontinued in 1997.
Feldstein [6] highlights that moral hazard results in the inefficient use of healthcare services and suggests that the introduction of co-payments is an effective way to reduce overutilization.
Such age-old techniques of sex selection are no doubt inefficient, but their presence today confirms indirectly the rather recent introduction of modern prenatal technology in the countryside.
"In particular, we believe the introduction of a capacity mechanism will make the British energy sector highly inefficient, costing consumers many billions in unnecessary cost".
Despite some consolidation and the introduction of some big-box retailers, the Japanese food-processing industry remains fragmented and inefficient because Japanese grocery stores are still mostly tiny mom-and-pop shops protected by strict land use laws.
In comparison with the inefficient control device using (2,2′-bipyridine)Eu DBM 3 as the red emitter in the same configuration, the introduction of difluorophenylene moiety into the Eu III) complex could possibly account for the improved performance of the title compound.
