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Interestingly, AdIKKβKA vector alone proved inefficient in reducing the viability of MCF7 cells, even at an MOI of 10,000 DNA particles/cell.
IKK inhibiting strategy alone proved inefficient in reducing the viability of MCF7 cells suggesting that an apoptotic stimulus was required in order to induce cell killing.
Although washing, peeling, and cooking remove a large amount of pesticides during food processing, some studies have indicated that they are inefficient in reducing pesticide residues below the MRL value.
They both target specific sequences in Trim17 mRNA but TRCN0000037335 appeared to be inefficient in reducing the level of endogenous Trim17 protein and was thus used as a negative control.
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Failings of deregulation are found to center around the following problems: high set-up cost; complicated market design; inevitable spot price volatility; market power abuse; inefficient investment; difficulty in reducing generation cost; dysfunctional input markets; stranded cost; unequal distribution of benefits.
On the other hand, bioenergy is heavily criticized as being inefficient in actually reducing carbon emissions and competing with other land uses [28].
This result demonstrates that the recirculating air filtration is especially effective in reducing exposure to UFPs even with a relatively inefficient air filter.
In-work benefits and public works are very cost-inefficient in terms of raising employment, but might be cost-efficient in reducing poverty and inequity.
In contrast, whereas TaXyn10A was efficient in reducing the inhibitory power of IOS, the enzyme was rather inefficient in doing so with the LF.
It is more likely that failure to secrete is due to a property of the protein to be expressed and reasons could include RNA instability, RNA secondary structure resulting in reduced translation levels, inefficient native signal peptides, susceptibility to proteolysis or the requirement of heterodimerisation for stability and secretion.
Six of 17 patients developed human anti-chimeric antibodies, resulting in reduced serum rituximab levels and inefficient B-cell depletion and less impressive efficacy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com