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HCV-specific CD8+ T-cells were not poly-functional which is consistent with the notion that although HCV-specific T-cells are found in hepatic tissue, their loss of poly-functionality may be associated with inefficient control of HCV replication.
A seminal study by Ly et al [21] demonstrated that one of the key elements in the protection of guinea pigs by BCG vaccination relates to production of IFNγ along with TNFα post-infection in comparison to the unvaccinated animals, wherein, excessive quantities of TNFα are produced in the absence of IFNγ resulting in an inefficient control of bacillary growth accompanied by excessive pathology.
We have concluded that rejection of MHC-II-/ lymph node transplants was due to inefficient control of T cell activation caused by impaired maintenance of regulatory T cells.
Inefficient control of hip rotation during this squat was of concern as it produces increased torsional stress on the knee joint, which was viewed as displacement of the knee from midline.
As ADHD is a disorder with qualitative and quantitative differences from severe mental illness such as the psychoses, we hypothesised that levels of the cytokine may be reduced reflecting inefficient control of the energy supply to active neuronal pathways.
Recent studies suggested that that the association between NTS and anaemia may be due to changes in neutrophil function as a result of changes in iron storage metabolism and subsequently inefficient control of pathogenic bacteria once they have entered the blood stream [ 17].
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We illustrate that traditional PVA approaches to managing predators for the benefit of prey can provide inefficient control recommendations.
The persistence of HRV shedding could be due to the inefficient immunological control of a single infectious episode.
This is caused both by inefficient stomatal control of transpiration and the change to a higher light intensity and lower humidity.
Preventive and therapeutic strategies remain very inefficient in the control of CA, most likely because of both pathogen-specific features and the lack of epidemiological data.
With unemployment at 7.7%, control of "inefficient and fragmented" training budgets is more important.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com