Sentence examples for inefficacy with from inspiring English sources

The majority of biologic switches related to inefficacy, with less than a quarter being related to drug related side effects/ intolerance.

Six of the nine observational studies included patients who had discontinued therapy with a TNF-α inhibitor for reasons other than inefficacy, with study percentages ranging between 12% (5 of 41 patients) and 100% (37 of 37 patients).

Ranking of all clinical evaluations conducted at weeks 0, 6, 14, and 22 showed that the DAS28 scores at weeks 14 and 22 are the most important measurements in predicting later withdrawal from infliximab therapy due to inefficacy, with ROC AUCs of 0.731 (standard error [SE] 0.06) and 0.706 (SE 0.06), respectively.

IA-treatment was assessed by means of a single blind comparison between IA-etanercept (E) and IA-placebo (P), administered once every two weeks for a 10-week period in all those patients not needing to drop-out because of drug inefficacy, with a cross-over after the first IA injection.

Despite the lack of clinical outcomes, Schnabel et al 9 reported that 27% of the patients who started with 15 mg/week needed a dose increase for inefficacy, compared with 3% of those who started with 25 mg/week (OR 10; 95% CI 2.9 to 33.3).

Bacteriophage treatment is particularly desirable because of the side effects and inefficacy associated with antibiotics and the emergence of new antibiotic-resistant strains.

In particular, effectiveness of methotrexate re-employment was lowest in patients who had been treated with 20 mg/week or more in the original course, but 60% of the patients originally treated with 12.5 17.5 mg/week did not experience inefficacy when treated with equal or lower doses upon re-employment.

While the public views inefficacy in Congress with disdain, the Republican leadership sees it as an accomplishment -- and as a weapon to use against the President's re-election.

Disappointment has also been reported due to the inefficacy of treatment with an ACEi in slowing progressive diabetic nephropathy when initiated in its early stage of microalbuminuria (20).

Among the 51 patients with inefficacy of the original methotrexate course, the drug was effectively re-employed in 23 (45.1%) patients (Table 2).

Switchers to a second anti-TNFα drug seem to have high treatment rates of continuation, and first drug withdrawal due to inefficacy is associated with an increased rate of a second drug withdrawal due to inefficacy but not toxicity; similarly, first drug withdrawal due to toxicity is associated with an increased rate of a second drug withdrawal due to toxicity but not inefficacy.