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When (beta_{2} = 0), the official message has no positive impact on the rumor spreading among the nonsupporter agents, and this is a scenario of inefficacy for the government communication.
That is, the initial density ratio is easily in the (URID) region, which means that a social crisis may occur under the scenario of inefficacy for the government communication.
The reason why systemic therapy like chemotherapy or immunotherapy is likely to be insufficient as the sole treatment is their relative inefficacy for solid tumours and the fact that clinical tumour burdens are large.
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Separate models were developed for overall discontinuation, for discontinuation due to inefficacy and for discontinuation due to adverse events.
In chronic CH the same regimen was commenced after the inefficacy of steroids for the previous three months was clinically demonstrated.
In France, physicians have repeatedly reported that unrealistic patient expectations, patient pressure to prescribe antibiotics, and insufficient time to educate patients about the inefficacy of antibiotics for upper respiratory tract infections are the major reasons why antibiotics are prescribed for these self-limiting diseases (12, 29, 36, 37).
Over a median of 2.0 years of follow-up (IQR=0.7 4.0, max 8.1) 50% of patients discontinued their primary anti-TNF therapy, including 22% for inefficacy and 21% for adverse events (table 2).
Further, response rates in a RCT of the newer biologic agent tocilizumab [ 52] were nearly identical for patients who discontinued treatment because of inefficacy or for unrelated reasons.
I'll take my gesticulating inefficacy home for an Easter egg, shall I?
Our data give a possible explanation for the inefficacy of EGFR inhibitors in phase II clinical trials for ERβ positive epithelioid MMe patients and opens the possibility of a more successful employment of these drugs in more aggressive, ERβ negative, tumors either as a single agent or in combination with Akt inhibitors.
In all cases three models were developed: (1) any stop, (2) stopping for inefficacy and (3) stopping for adverse events.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com