The efficacy objective is to find preliminarily evidence of the effectiveness or ineffectiveness of study treatments.
If clinical complete response was observed in less than 17 patients, the trial was considered closed due to ineffectiveness of studied regimen.
In these studies, ineffectiveness of nurse-midwives' work placement coupled with the lack of training opportunities, and the lack of learning resources, resulted in substandard care for pregnant women [ 22, 23].
Some studies report the ineffectiveness of intervention [ 47], while others report that cessation rates were 2-3 times higher in the intervention group [ 48].
Therefore, the ineffectiveness of LGG in the study of Prantera et al. [ 50] cannot predict the inefficacy of L. johnsonii LA1 and cannot predict the inefficacy of other single strains in future trials [ 50].
zVAD.fmk does not inhibit neutrophil apoptosis at concentrations below 100 µM (Figure 1), suggesting the ineffectiveness of zVAD.fmk in previously published studies may be a feature of the higher concentrations required in neutrophils compared to other cell types.
Jorissen et al reported that one possibility for the ineffectiveness of SB-PS in their study was due to degradation of the PS with time.
Some researchers indicated that the relative ineffectiveness of dantrolene in some of the studies may be related to an inadequate dose [ 21, 47].
A number of past studies have shown ineffectiveness of a two-fold cut-off as the basis for filtering out DEGs [ 24- 26] and low-magnitude transcriptional changes have been found to produce functionally significant changes [ 27- 29].
With regard to pandemic influenza, hand hygiene and other hygiene measures in schools should remain a component in the range of public health measures during an influenza pandemic, unless future studies demonstrate the ineffectiveness of hand hygiene to specifically reduce the transmission of influenza.
The majority of participants believed that the lack of studies proving the effectiveness of the drops was not neccessarily proof of ineffectiveness.
