It is important to note that the depth of styrene is limited when the initiator BPO is added along with styrene, providing a good explanation for the previously reported ineffective solid-state modification of melt-extruded iPP pellets.
Because of the addition of Li-ion conducting liquid between the solid electrode and solid electrolyte, the hybrid electrolyte cell minimizes the ineffective solid-on-solid interfaces common in all-solid-state cells.
However, HDACi remain ineffective against solid tumors and are associated with adverse events including cardiotoxicity.
Triapine is an α- N-heterocyclic thiosemicarbazone with promising anticancer activity against hematologic malignancies but widely ineffective against solid tumor types in clinical trials.
The underlying mechanism of NK cell antitumour may lie in efficient elimination of CTC and preventing metastatic dissemination, although they are ineffective in primary solid tumours and distant metastases.
However, despite promising activity against leukemia [1,2], Triapine has proven ineffective against a variety of solid malignancies [3 5].
However, several clinical phase II studies revealed that Triapine is ineffective against a variety of solid tumors including advanced adenocarcinoma of the pancreas [3], non-small-cell lung cancer [4], and renal cell carcinoma [5].
Popular techniques such as feeding them grits, the hot breakfast cereal popular in the South, have now been proved ineffective; fire ants don't eat solid food.
At steady operation the catalyst surface temperatures exceeded by 200 K the adiabatic equilibrium temperature and standard (passive) heat transfer mechanisms in the solid were shown to be ineffective in providing proper reactor thermal management.
In order to avoid the detailed 3D modelling of nails (or screws) using solid elements, which is costly ineffective, the authors proposed and developed an approach based on beam-to-solid coupling where the nails (or screws) were modelled using one-dimensional beam element, while the assembled timber members were modelled using solid elements.
Indeed, clinical trials utilizing high-dose chemotherapy for solid tumors have been largely ineffective with limited clinical benefit.
