Sentence examples for ineffective signals from inspiring English sources

Another strategy of potentially equal adaptive value might be to reduce signaling investment in antagonistic environments to minimize costs of ineffective signals (Järvenpää and Lindström 2004; Heuschele et al. 2009).

During EBOV infection, we can speculate that T/DC synapsis is ineffective as it is characterized by TCR/MHC-peptide recognition (signal 1) in a high inflammatory microenvironment (deregulated signal 3) but in absence of co-stimulatory accessory molecules on DC surface (ineffective signal 2).

Therefore, we reasoned that impaired activation of Bid or ineffective Trail signaling may contribute to the accelerated tumor formation observed in Caspase-2-deficient mice overexpressing c-Myc.

Immunosuppressed individuals might express alterations of immune function such as reduced antibody production, decreased immune cell counts, or ineffective cell signaling.

Characterization of the distinct engraftment phenotypes by genome wide expression analysis revealed genes coding for molecules involved in apoptosis regulation pointing to ineffective apoptosis signaling in TTLshort/poor outcome ALL.

More specifically, the Americans wanted the ability to jam Galileo without rendering GPS signals ineffective.

However, these algorithms are usually computationally demanding or ineffective under low signal-to-noise ratio (SNR).

Moreover, it is ineffective at driving signal transduction, as revealed by its low capacity to stimulate intracellular calcium mobilization, weak chemotactic activity and lack of effect on progenitor cell survival [17].

Taken together, the observed deficits in keeping task-sets online and flexibly switching between task-sets may not be due to top-down control failure, but rather ineffective bottom-up signaling for the need for control.

These data suggest that soluble PD-1 may protect autoreactive T cells from undergoing apoptosis and corroborate the idea that ineffective PD-1 signaling is an important contributor to RA susceptibility.

This makes the number of components estimation based on the global Rényi entropy ineffective for real-world signals.